LA CIENCIA DE DryUp®
Raíz de diente de león
Se ha demostrado en investigaciones que la raíz de diente de león, un ingrediente diurético clásico, aumenta la producción de orina, lo que provoca la eliminación del exceso de agua corporal sin afectar los niveles de potasio en el músculo, siendo naturalmente rica en potasio1. Algunos estudios incluso han comparado la actividad diurética de la raíz del diente de león para que sea comparable a la del diurético recetado furosemida2.
Extracto de cola de caballo
También conocido como Equistum arvense, es una hierba tradicional que se ha utilizado históricamente como diurético y que se ha utilizado tradicionalmente para eliminar el agua no deseada aumentando la cantidad de agua y sal liberada por la orina. Sorprendentemente, recientemente se demostró en un pequeño estudio que la cola de caballo puede ser tan eficaz como la hidroclorotiazida como diurético sin la pérdida de electrolitos asociada3.
Uva Ursi
Uva ursi, conocido formalmente como Arctostaphylos Uva-ursi es una hierba tradicional que no sólo se ha utilizado con fines diuréticos, sino para la salud urinaria en general. Uva ursi brilla particularmente en materia de salud urinaria cuando se utiliza para el tratamiento de la prevención de infecciones del tracto urinario atribuidas a su principal bioactivo, la arbutina que crea un metabolito llamado glucurónido de hidroquinona que impide que las bacterias se adhieran a los tejidos4.
Bayas de enebro
Juniperus communis, commonly known as Juniper berry is a traditional berry extract that is known for not only being a gentle diuretic, but also for its properties that specifically can help reduce bloating, complimenting other diuretics in a formula. It is also a potent antioxidant that protects from free-radical damage at a cellular level, complimenting the formula as a whole5.
Taurine
Taurine is considered a conditionally essential amino acid, that isn’t used for protein synthesis, but rather for components of the nervous system. It is vital for the function in muscle tissues that works by stabilizing cell membranes and supporting the proper transport of the electrolytes potassium, calcium, magnesium and sodium into and of out cells6. This makes it an ideal addition to DryUp to complement the electrolyte matrix we have included.
Calcium
One of the most well-known minerals, calcium is important for many things including proper neuromuscular and vascular function, normal blood clotting function, neurotransmission and cell signaling. It is important in the contraction of muscle as calcium ions is what triggers the process in muscle contraction7.
Magnesium
An important electrolyte, magnesium is responsible for a variety of important functions including the support of energy production, proper enzyme function. It is also crucial for muscle function as it acts like a natural calcium blocker to help muscle relax by allowing calcium re-uptake8.
Potassium
Considered by many to be the ‘king’ of both preventing and treating muscle cramping, the essential mineral potassium is a vital electrolyte for maintaining proper muscle function. Some of these vital muscle functions include contraction, proper pH in the body, nerve transmission and fluid regulation. It is also a vital part of ATP production, so when shedding water, it is especially to make sure potassium is replenished to maintain proper functions9.
Gamma Butyrobetaine
Known by some as a ‘super carnitine’, gamma butyrobetaine is a carnitine precursor that is converted into l-carnitine through an enzyme called Gamma-butyrobetaine dioxygenase which signals the body toe produce its own carnitine10. Some research shows that it can nearly double plasma carnitine levels following ingestion of GBB. It has positive benefits for nitric oxide production and has an exothermic effect in the body, leading to some of the best sweat sessions of your life at the gym or during cardio11.
Afromomum melegueta
Known also as “Grains of Paradise”, this spice is similar to ginger and has been shown in research to be a strong body recomposition aid. Containing the extracts 6-gingerol and 6-paradol, Afromomum melegueta has been shown to decrease visceral fat and increase calorie burn, a potent 1-2 thermogenic punch. It achieves these effects via promoting the transformation of white adipose tissue into brown adipose tissue, which yields greater energy expenditure12.
Scientific References
1. Clare B. The diuretic effect in human subjects of an extract of Taraxacum officinale folium over a single day. J Complement Altern Med. 2009;15(8):929-934. doi:10.1089/acm.2008.0152
2. Racz-Kotilla E. The action of Taraxacum officinale extracts on the body weight and diuresis of laboratory animals. Planta Med. 1974;26(3):212-217.
3. Carneiro D. Randomized, Double-Blind Clinical Trial to Assess the Acute Diuretic Effect of Equisetum arvense (Field Horsetail) in Healthy Volunteers. J Evid Based Complement Altern Med. 2014;2014. doi:10.1155/2014/760683
4. Schindler G. Urinary excretion and metabolism of arbutin after oral administration of Arctostaphylos uvae ursi extract as film-coated tablets and aqueous solution in healthy humans. J Clin Pharmacol. 2002;42(8):920-927. doi:10.1177/009127002401102740
5. El-Ghorab A. Chemical composition of volatile extract and biological activities of volatile and less-volatile extracts of juniper berry (Juniperus drupacea L.) fruit. J Agric Food Chem. 2008;56(13):5021-5025. doi:10.1021/jf8001747
6. Schaffer S. Physiological roles of taurine in heart and muscle. J Biomed Sci. 2010;17(Suppl 1). doi:10.1186/1423-0127-17-S1-S2
7. Szent-Gyorgyi A. Calcium regulation of muscle contraction. Biophys J. 1975;15(7):702-723. doi:10.1016/S0006-3495(75)85849-8
8. Jahnen-Dechent W. Magnesium basics. Clin Kidney J. 2012;5(Suppl 1):i3-i14. doi:10.1093/ndtplus/sfr163
9. Weaver C. Potassium and Health. J Adv Nutr. 2013;4(3):368S-377S. doi:10.3945/an.112.003533
10. Rebouche C. Utilization of Dietary Precursors for Carnitine Synthesis in Human Adults. J Nutr. 1989;119(12):1907-1913. doi:10.1093/jn/119.12.1907
11. Sjakste N. Endothelium- and nitric oxide-dependent vasorelaxing activities of gamma-butyrobetaine esters: possible link to the antiischemic activities of mildronate. Eur J Pharmacol. 2004;495(1):67-73.
12. Sugita J. Grains of paradise (Aframomum melegueta) extract activates brown adipose tissue and increases whole-body energy expenditure in men. Br J Nutr. 2013;110(4):733-738. doi:10.1017/S0007114512005715
